Puedes agregar este u otros regtweaks a la seccion de [base.Tweaks.AddReg] en ie.inf
;Skip First Run Settings HKCU,"Software\Microsoft\Internet Explorer\Main","IE8RunOnceLastShown",0x10001,1 HKCU,"Software\Microsoft\Internet Explorer\Main","IE8RunOnceLastShown_TIMESTAMP",0x1,10,5b,dd,f1,61,df,cd,01 HKCU,"Software\Microsoft\Internet Explorer\Main","IE8RunOncePerInstallCompleted",0x10001,1 HKCU,"Software\Microsoft\Internet Explorer\Main","IE8TourShown",0x10001,1
;Hide Menu Bar HKCU,"SOFTWARE\Microsoft\Internet Explorer\Main","AlwaysShowMenus",0x10001,0
;Hide Favorite Bar HKCU,"SOFTWARE\Microsoft\Internet Explorer\LinksBar","Enabled",0x10001,0
;Force Internet Explorer Menu Bar to Top (above the address bar) HKCU,"Software\Microsoft\Internet Explorer\Toolbar\WebBrowser","ITBar7Position",0x10001,1
;Prevents the prompt to install Windows Search 4 when typing in the address bar. HKCU,"Software\Microsoft\Internet Explorer\Main\WindowsSearch","ShowPrompt",0x10001,0
;Hide compatibility view button on address bar HKCU,"Software\Microsoft\Internet Explorer\CommandBar","ShowCompatibilityViewButton",0x10001,0
;Tabbedbrowsing settings ;Do not switch to new opened tab(s) HKLM,"Software\Microsoft\Internet Explorer\TabbedBrowsing","OpenInForeground",0x10001,0 ;Always open a new page in a new tab instead of a new window HKLM,"Software\Microsoft\Internet Explorer\TabbedBrowsing","PopupsUseNewWindow",0x10001,2
;Disable playing sound and displaying message when a popup is blocked: HKCU,"Software\Microsoft\Internet Explorer\New Windows","PlaySound",0x10001,0 HKCU,"Software\Microsoft\Internet Explorer\New Windows","UseSecBand",0x10001,0