It works perfectly ! thanks Detailled step for interested users: Download ricktendo Adobe reader msi (ex: AdbeRdrLite11006_fr_FR.msi) Download and install Adobe Customization Wizard XI Open AdbeRdrLite11006_fr_FR.msi in Adobe Customization Wizard, Uncheck "When launching PDF in Internet Explorer, prompt user with Open/Save dialog" Click to "Transform -> Generate transform" and save a "nopopup.mst" file Download and install InstEd Click on your "nopopup.mst" file and choose the AdbeRdrLite11006_fr_FR.msi file Finally, generate the new custom msi with "File -> Save As" (ex: AdbeRdrLite11006_fr_FR_nopopup.msi)