Sending reported error (0x80042109)
I’ve received the following error for all my accounts on a fresh installation of Outlook 2010.
Sending reported error (0x80042109): ‘Outlook cannot connect to your outoing (SMTP) e-mail server. If you continue to receive this message, contact your server administrator or Internet service provider (ISP).’
Solution:
I’ve noticed that Microsoft has changed the default SMTP port in Outlook 2010 from 25 to 587 as you can see in the picture below.
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So, if your ISP’s SMTP server does not allow port 587, you won’t be able to send e-mails until you change the SMTP port to 25.


You F’in ROCK!!! For six F’IN days I’ve been trying to figure this out, changing MacAfee settings, etc. Once I changed this to 587 all the sudden it works!
Thank you, I found changing it to 587 worked for me too. Sadly after buying online one of those “fixes” online that did nothing!